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Domino's Wisconsin 6 Cheese Pizza, X-Large 16" Hand Tossed Nutrition Facts

One serving of Domino's Wisconsin 6 Cheese Pizza, X-Large 16" Hand Tossed (1 slice (1/8 pizza, 161 g)) has 440 calories, 19g of protein, 46g of carbohydrates (44g net carbs), 19g of fat and 880mg of sodium.

About 18% of its calories come from protein, 43% from carbs and 40% from fat.

How it compares with other specialty pizzas (per slice)

Among 44 items in Specialty Pizzas (per slice), it ranks #37 for fewest calories and #8 for most protein. Showing the closest items by calories.

Related Domino's guides

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Nutrition Facts

Serving: 1 slice (1/8 pizza, 161 g)

Calories440

% Daily Value*

Total Fat 19g
24%
Saturated Fat 10g
50%
Trans Fat 0.5g
Cholesterol 50mg
17%
Sodium 880mg
38%
Total Carbohydrate 46g
17%
Dietary Fiber 2g
7%
Total Sugars 4g
Protein 19g
38%

* Percent Daily Values are based on a 2,000 calorie diet. Figures are estimates from published restaurant data; actual portions vary by location.

Source: Domino's Nutrition Guide, US (August 2026), checked August 2026.