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Domino's Ultimate Pepperoni Pizza, Small 10" Hand Tossed Nutrition Facts

One serving of Domino's Ultimate Pepperoni Pizza, Small 10" Hand Tossed (1 slice (1/4 pizza, 131 g)) has 380 calories, 16g of protein, 38g of carbohydrates (37g net carbs), 18g of fat and 850mg of sodium.

About 17% of its calories come from protein, 40% from carbs and 43% from fat.

How it compares with other specialty pizzas (per slice)

Among 44 items in Specialty Pizzas (per slice), it ranks #22 for fewest calories and #24 for most protein. Showing the closest items by calories.

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Nutrition Facts

Serving: 1 slice (1/4 pizza, 131 g)

Calories380

% Daily Value*

Total Fat 18g
23%
Saturated Fat 8g
40%
Trans Fat 0g
Cholesterol 40mg
13%
Sodium 850mg
37%
Total Carbohydrate 38g
14%
Dietary Fiber 1g
4%
Total Sugars 3g
Protein 16g
32%

* Percent Daily Values are based on a 2,000 calorie diet. Figures are estimates from published restaurant data; actual portions vary by location.

Source: Domino's Nutrition Guide, US (August 2026), checked August 2026.