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Domino's Buffalo Chicken Sandwich Nutrition Facts

One serving of Domino's Buffalo Chicken Sandwich (1/2 Sandwich) has 420 calories, 19g of protein, 36g of carbohydrates (36g net carbs), 22g of fat and 1,250mg of sodium.

About 18% of its calories come from protein, 34% from carbs and 47% from fat.

How it compares with other oven-baked sandwiches

Among 5 items in Oven-Baked Sandwiches, it ranks #3 for fewest calories and #4 for most protein.

ItemCalProteinCarbsFatSodium
Buffalo Chicken Sandwich42019g36g22g1,250mg
Chicken Bacon Ranch Sandwich47022g35g26g1,170mg
Chicken Parm Sandwich41024g36g19g1,030mg
Italian Sandwich42020g35g22g1,520mg
Philly Cheese Steak Sandwich37018g37g17g1,200mg

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Nutrition Facts

Serving: 1/2 Sandwich

Calories420

% Daily Value*

Total Fat 22g
28%
Saturated Fat 7g
35%
Trans Fat 0g
Cholesterol 55mg
18%
Sodium 1,250mg
54%
Total Carbohydrate 36g
13%
Dietary Fiber 0g
0%
Total Sugars 2g
Protein 19g
38%

* Percent Daily Values are based on a 2,000 calorie diet. Figures are estimates from published restaurant data; actual portions vary by location.

Source: Domino's Nutrition Guide, US (August 2026), checked August 2026.